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1.
Article Ru | MEDLINE | ID: mdl-25473664

The article presents an overview of scientific publications devoted to the study of epidemiology, etiology, clinical manifestations and basic approaches to the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in children. An analysis of the results shows a high frequency of comorbidity between ADHD and emotional disorders (anxiety) that determines the severity of the main clinical symptoms and leads to severe social maladaptation. Inclusion of anxiolytics and nootropics in treatment of ADHD is required.


Anxiety Disorders/epidemiology , Attention Deficit Disorder with Hyperactivity/epidemiology , Mood Disorders/epidemiology , Anti-Anxiety Agents/therapeutic use , Anxiety/drug therapy , Anxiety/epidemiology , Anxiety Disorders/drug therapy , Attention Deficit Disorder with Hyperactivity/diagnosis , Attention Deficit Disorder with Hyperactivity/drug therapy , Child , Comorbidity , Humans
2.
Ter Arkh ; 86(12): 61-5, 2014.
Article Ru | MEDLINE | ID: mdl-25804042

AIM: To study cognitive and emotional impairments in patients with anxiety-phobic disorders (APDs), to comparatively analyze the clinical manifestations of acute (less than one-year) and protracted (1-to-5-year) forms of this disease, and to evaluate the efficacy of noofen used to treat this pathology. SUBJECTS AND METHODS: Sixty-two patients aged 18 to 50 years with APDs were examined. The investigators collected clinical history data, performed neurological examination, and assessed autonomic disorders in accordance with the questionnaire to reveal their signs, anxiety using the Hamilton anxiety rating scale, memory impairment employing the methods developed by A.R. Luria, attention disorders applying the test of variables of attention, and diagnosed emotional intelligence using the Mayer-Salovey-Caruso emotional intelligence test. Noofen 1000 mg/day was used to treat the patients. RESULTS: Protracted APDs were shown to be characterized by the higher degree of psychosomatic symptoms and by more pronounced impairments in attention, memory, and emotional intelligence. The data of posttreatment clinical and psychological studiesare indicative of improvements in 73.3% of cases. CONCLUSION: The findings may lead to the conclusion that noofen is highly effective in the treatment of patients with protracted APDs.


Cognition Disorders , Phobic Disorders , Tranquilizing Agents/pharmacology , gamma-Aminobutyric Acid/analogs & derivatives , Acute Disease , Adolescent , Adult , Chronic Disease , Cognition Disorders/drug therapy , Cognition Disorders/etiology , Cognition Disorders/physiopathology , Humans , Middle Aged , Phobic Disorders/complications , Phobic Disorders/drug therapy , Phobic Disorders/physiopathology , Tranquilizing Agents/administration & dosage , Treatment Outcome , Young Adult , gamma-Aminobutyric Acid/administration & dosage , gamma-Aminobutyric Acid/pharmacology
3.
Article Ru | MEDLINE | ID: mdl-25726788

OBJECTIVE: To study clinical/psychological characteristics of neurasthenia and residual asthenia and to assess the efficacy of noofen and adaptol in the treatment of these disorders. MATERIAL AND METHODS: Authors examined 30 adolescents with neurasthenia and 30 with residual asthenia. The Multidimensional Fatigue Inventory (MFI-20), A.M. Vein questionnaire, Spilberger-Khanin questionnaire, The Test of Variables of Attention (TOVA) were used. Patients were divided into two equal groups (n=30), each included 15 patients with residual asthenia and neurasthenia. Patients of the first group received adaptol in dosage 1000 mg daily and patients of the second group received noofen in dosage 500 mg daily. The duration of the study was 30 days. RESULTS AND CONCLUSION: The significantly higher levels of fatigue, inattention and exhaustibility were identified in patients with residual asthenia. Adolescents with neurasthenia were characterized by higher anxiety. The higher efficacy of adaptol in treatment of neurasthenia (80% in adolescents with neurasthenia and 60% of patients with residual asthenia) was shown. Noofen was more effective in treatment of residual asthenia (66.7% of adolescents with neurasthenia and 86.7% with residual asthenia.


Anti-Anxiety Agents/therapeutic use , Asthenia/diagnosis , Asthenia/drug therapy , Biureas/therapeutic use , GABA Agonists/therapeutic use , Neurasthenia/diagnosis , Neurasthenia/drug therapy , gamma-Aminobutyric Acid/analogs & derivatives , Adolescent , Anxiety/diagnosis , Anxiety/drug therapy , Fatigue/diagnosis , Fatigue/drug therapy , Female , Humans , Male , Psychiatric Status Rating Scales , Self-Assessment , Surveys and Questionnaires , Treatment Outcome , gamma-Aminobutyric Acid/therapeutic use
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